Abstract: In this paper, the dielectric properties of NaCl solutions with different concentrations are measured and calculated by several commonly used analysis and calculation models of the coaxial measurement of dielectric properties of biological tissue in the frequency range of 100 MHz to 1 GHz. Based on the results, these models are compared in terms of scope of application, analysis and calculation complexity, accuracy and stability. According to the actual measurement results, the calculation error of the equivalent circuit model with radiation term is low, and the calculation stability is high. But it requires the high standard materials for determining the model parameters. The equivalent circuit model without radiation term is easy to understand and simple to calculate, but the calculation error needs to be improved. It means that the calculation result of this model is greatly affected by the measured object and the measurement frequency, and the better standard materials are also required to determine its parameters. The quasi-static field analysis model does not require the standard materials to determine the parameters, but the analysis process of these models is more complicated, the calculation is timeconsuming, and the stability of the calculation results is insufficient. In summary, based on the results of this study, it can provide a reliable reference for the selection of the analysis and calculation models for the high-frequency coaxial measurement of the dielectric properties of biological tissues.