Abstract: The paper designs a small and compact coplanar waveguide-fed dual-frequency implanted antenna with a size of 10 mm×10 mm×1.27 mm for biomedical applications. The antenna works in the Industrial Scientific Medical (ISM) low frequency band (433~434. 8 MHz) and Wireless Medical Telemetry Service (WMTS) frequency bands (1.395~1.40 GHz). The designed antenna adopts coplanar waveguide feeding easily integrated with other structures. It adopts high dielectric constant dielectric substrate and folded meandering dipole-like structure to reduce the size of the antenna effectively. Under the premise of meeting the SAR (Specific Absorption Rate) value standard, the U-shaped grounding plate is used to obtain higher gain. The highest gains at the resonance frequencies in the two frequency bands are -32.23 dBi and -20.63 dBi respectively, which ensures the performance of the antenna. Finally, the actual antenna is made based on simulation results for testing, and the measured data is in good agreement with the simulation results. The research results can provide an important reference for the development and application of implantable antennas.