Abstract: To improve the reliability of RFID system embedded in tire, it needs to solve a couple of contradictions. In one hand, in order to ensure the tags and tires is good adhesion and binding, the size of antenna of tags should be small enough. In the other hand, the radio environment of tiers is not ideal. Because tire has intrinsic dielectric loss and disturbs electromagnetic wave, the size of antenna of tags should be large enough so as to improve the ability of electromagnetic radiation. The methods before of design for tag antenna are complex and are not suited to bind the tags and tires. According to the Bode-Fano impedance match limitations, using periodicity and compactedness of meander line, a design method with the miniaturized UHF RFID tag meander line embedded in tire is presented. The method is simple, has good impedance match properties and bind properties. Also, a miniaturized UHF RFID tag meander line antenna embedded in tire is designed,where the size of the tag antenna is limited. The result of HFSS simulation shows that the tag antenna's return loss is less than -10dB in 833 ~971MHz, which covers USA bandwidth 902 ~928MHz . The biggest gain is 2. 4dBi. Eventually, the result of experiment shows, the identification probability is almost larger than 80% when the read distance is less than 90cm,and it is larger than 90% when the read distance is less than 50cm. Besides, it has good bind properties between tags and tires. So it meets the requirements of design.